1. RFP : 기후변화 매개체 방제법 및 방제 시나리오 개발

2. 해당분과 : 2-2-3 과제

3. 과제명 : SFTS 바이러스를 매개하는 작은소참진드기 방제를 위한 살비제/기피제 개발

4. 연구책임자 : 이회선(전북대학교)

[Abstract]

Acaricidal activities of the active component isolated from Melissa officinalis oil and its structural analogues against Tyrophagus putrescentiae were evaluated using fumigant and contact bioassays. The structure of 3,7-dimethyl-2,6-octadienal purified from M. officinalis oil was elucidated with EI-MS, 1H- and 13C-NMR, 1H-1H COSY, and DEPT-NMR. Based on the LD50 values of 3,7-dimethyl-2,6-octadienal analogues in fumigant and contact bioassays, respectively, 2,4-octadienal showed the highest activity (LD50 = 2.09 µg/cm3 and 11.08 µg/cm2), followed by 3,7-dimethyl-6-octenal(3.60 µg/cm3 and 29.34 µg/cm2), 3,7-dimethyl-2,6-octadienal (6.18 µg/cm3 and 36.17 µg/cm2), 2-octenal (7.45 µg/cm3 and 47.36 µg/cm2) and M. officinalis oil (8.89 µg/cm3 and 23.83 µg/cm2). Comparing the acaricidal activities of the aldehyde group based on the degree of unsaturation, 2,4-octadienal containing two double bonds was more potent than 2-octenal with a single double bond. Based on the acaricidal activities of the methyl group, on the other hand, 3,7-dimethyl-6-octenal containing a single double bond was more acaricidal than 3,7-dimethyl-2,6-octadienal with two double bonds. These results indicate that 3,7-dimethyl-2,6-octadienal analogues are useful to control food mites.